PTDSS1 P48651

磷脂酰丝氨酸合酶1 (PSS-1) (PtdSer合酶1) (EC 2.7.8.29) (丝氨酸交换酶I)

蛋白质信息 (UniProt)

磷脂酰丝氨酸合酶1 (PSS-1) (PtdSer合酶1) (EC 2.7.8.29) (丝氨酸交换酶I)

P48651

功能描述

催化碱基交换反应，在该反应中磷脂酰乙醇胺(PE)或磷脂酰胆碱(PC)的极性头部基团被L-丝氨酸取代 (PubMed:19014349, PubMed:24241535)。主要催化磷脂酰胆碱的转化 (PubMed:19014349, PubMed:24241535)。在体外也能转化磷脂酰乙醇胺，但程度较低 (PubMed:19014349, PubMed:24241535)。 {ECO:0000269|PubMed:19014349, ECO:0000269|PubMed:24241535}。

亚细胞定位

Endoplasmic reticulum membrane

关键词

3D-structure Acetylation Alternative splicing Disease variant Dwarfism Endoplasmic reticulum Intellectual disability Lipid biosynthesis Lipid metabolism Membrane

外部链接

UniProt: P48651

NCBI Gene

GeneCards