前列腺蛋白 (EC 3.4.21.-) (通道激活蛋白酶 1) (CAP1) (丝氨酸蛋白酶 8) [切割为：前列腺蛋白轻链; 前列腺蛋白重链]
前列腺蛋白 (EC 3.4.21.-) (通道激活蛋白酶 1) (CAP1) (丝氨酸蛋白酶 8) [切割为：前列腺蛋白轻链; 前列腺蛋白重链]
Q16651功能描述
具有胰蛋白酶样切割特异性，偏好多碱性底物。通过γ亚基 (SCNN1G) 的激活性切割刺激上皮钠通道 (ENaC) 活性。 {ECO:0000269|PubMed:15246975, ECO:0000269|PubMed:15474520}。
组织特异性
Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
亚细胞定位
[Prostasin]: Cell membrane; Single-pass membrane protein.; SUBCELLULAR LOCATION: [Prostasin light chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.; SUBCELLULAR LOCATION: [Prostasin heavy chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
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