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PRKAR1A P10644

I型α cAMP依赖性蛋白激酶调节亚基 (组织特异性熄灭因子1) (TSE1)

蛋白质信息 (UniProt)

I型α cAMP依赖性蛋白激酶调节亚基 (组织特异性熄灭因子1) (TSE1)

P10644

功能描述

cAMP依赖性蛋白激酶的调节亚基,参与细胞内的cAMP信号传导。 {ECO:0000269|PubMed:16491121, ECO:0000269|PubMed:20215566, ECO:0000269|PubMed:26405036}.

组织特异性

Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

亚细胞定位

Cell membrane

关键词

3D-structure Acetylation Alternative splicing cAMP cAMP-binding Cell membrane Cushing syndrome Direct protein sequencing Disease variant Disulfide bond