脯氨酰内肽酶样 (EC 3.4.21.-) (脯氨酰内肽酶样)
脯氨酰内肽酶样 (EC 3.4.21.-) (脯氨酰内肽酶样)
Q4J6C6功能描述
丝氨酸肽酶，其精确的底物特异性尚不清楚 (PubMed:16143824, PubMed:16385448, PubMed:28726805)。不在精氨酸或赖氨酸残基后切割肽段 (PubMed:16143824)。通过调节AP-1复合物的膜结合来调节反式高尔基体网络形态和分选 (PubMed:23321636)。可能在突触囊泡胞吐作用的调节中发挥作用 (PubMed:24610330)。 {ECO:0000269|PubMed:16143824, ECO:0000269|PubMed:16385448, ECO:0000269|PubMed:23321636, ECO:0000269|PubMed:24610330, ECO:0000269|PubMed:28726805}。
组织特异性
Expressed in pyramidal neurons of the temporal cortex and neocortex (at protein level) (PubMed:23485813). Widely expressed (PubMed:15913950, PubMed:16385448). Expressed at higher level in brain, skeletal muscle, heart and kidney (PubMed:15913950, PubMed:16385448). Expressed at the endplates in the neuromuscular junction (PubMed:24610330).
亚细胞定位
Cytoplasm, cytosol
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