PPRC1 Q5VV67

过氧化物酶体增殖物激活受体γ辅激活相关蛋白1 (PGC-1相关辅激活因子) (PRC)

蛋白质信息 (UniProt)

过氧化物酶体增殖物激活受体γ辅激活相关蛋白1 (PGC-1相关辅激活因子) (PRC)

Q5VV67

功能描述

在线粒体生物发生和细胞生长相关的核基因转录激活过程中作为共激活因子。参与CREB和NRF1靶基因的转录共激活。 {ECO:0000269|PubMed:11340167, ECO:0000269|PubMed:16908542}。

组织特异性

Strongly expressed in heart and skeletal muscle, moderately in lung, placenta, intestine, liver, kidney, spleen, thymus, colon and brain. Also expressed in several oncocytic thyroid tumors.

亚细胞定位

Nucleus

关键词

Activator Alternative splicing Nucleus Phosphoprotein Proteomics identification Reference proteome RNA-binding Transcription Transcription regulation

外部链接

UniProt: Q5VV67

NCBI Gene

GeneCards