蛋白酶体成熟蛋白 (Proteassemblin) (蛋白质UMP1同源物) (hUMP1) (电压门控钾通道β亚基4.1)
蛋白酶体成熟蛋白 (Proteassemblin) (蛋白质UMP1同源物) (hUMP1) (电压门控钾通道β亚基4.1)
Q9Y244功能描述
标准蛋白酶体和免疫蛋白酶体组装所必需的分子伴侣。在蛋白酶体成熟完成后被降解。介导20S前蛋白酶体与内质网的结合。 {ECO:0000269|PubMed:15944226, ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17948026}.
组织特异性
Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer.
亚细胞定位
Cytoplasm, cytosol. Nucleus. Microsome membrane.
关键词