PNPLA4 P41247

含Patatin样磷脂酶结构域蛋白4 (EC 3.1.1.3) (钙非依赖性磷脂酶A2-eta) (iPLA2-eta) (EC 3.1.1.4) (GS2蛋白)

蛋白质信息 (UniProt)

含Patatin样磷脂酶结构域蛋白4 (EC 3.1.1.3) (钙非依赖性磷脂酶A2-eta) (iPLA2-eta) (EC 3.1.1.4) (GS2蛋白)

P41247

功能描述

具有丰富的三酰甘油脂肪酶活性 (PubMed:15364929, PubMed:16150821, PubMed:17603008)。将脂肪酸从甘油三酯转移至视黄醇，水解视黄酯，并从甘油三酯生成1,3-二酰甘油 (PubMed:17603008)。此外，还具有酰基甘油转酰基酶和磷脂酶A2活性 (PubMed:15364929, PubMed:17603008)。 {ECO:0000269|PubMed:15364929, ECO:0000269|PubMed:16150821, ECO:0000269|PubMed:17603008}。

组织特异性

Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen.

亚细胞定位

Mitochondrion

关键词

Alternative splicing Hydrolase Lipid degradation Lipid metabolism Mitochondrion Primary mitochondrial disease Proteomics identification Reference proteome

外部链接

UniProt: P41247

NCBI Gene

GeneCards