黑素浓集激素原 [裂解为：神经肽-甘氨酸-谷氨酸 (NGE) (神经肽 G-E)；神经肽-谷氨酸-异亮氨酸 (NEI) (神经肽 E-I)；黑素浓集激素 (MCH)]
黑素浓集激素原 [裂解为：神经肽-甘氨酸-谷氨酸 (NGE) (神经肽 G-E)；神经肽-谷氨酸-异亮氨酸 (NEI) (神经肽 E-I)；黑素浓集激素 (MCH)]
P20382功能描述
MCH可能作为神经递质或神经调质参与广泛的神经元功能，这些功能旨在调节目标导向行为，如食物摄入，以及一般觉醒。也可能在精母细胞分化中发挥作用。
组织特异性
Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood. In brain exclusively mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly.
亚细胞定位
Secreted.
关键词