PLK5 Q496M5

无活性丝氨酸/苏氨酸蛋白激酶PLK5 (Polo样激酶5) (PLK-5)

功能描述

无活性的丝氨酸/苏氨酸蛋白激酶，在细胞周期进程和神经元分化中发挥作用。 {ECO:0000269|PubMed:21245385}。

组织特异性

Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level).

亚细胞定位

Nucleus, nucleolus