PARD3B Q8TEW8

分区缺陷蛋白3同源物B (肌萎缩侧索硬化2染色体区域候选基因19蛋白) (PAR3-beta) (分区缺陷蛋白3样蛋白) (PAR3-L蛋白)

功能描述

推定的衔接蛋白，参与不对称细胞分裂和细胞极化过程。可能在上皮紧密连接的形成中发挥作用。

组织特异性

Highly expressed in kidney, lung and skeletal muscle. Expressed at intermediate levels in brain, heart, placenta, liver and pancreas. Isoform 1 is predominant, while isoform 2 and isoform 3 are expressed at lower levels.

亚细胞定位

Endomembrane system. Cell junction. Cell junction, tight junction. Note=Partially localized along the cell-cell contact region. Colocalizes with TJP1 to epithelial tight junctions.