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P4HA1 P13674

脯氨酰4-羟化酶亚基α-1 (4-PH alpha-1) (EC 1.14.11.2) (前胶原-脯氨酸,2-氧戊二酸-4-双加氧酶亚基α-1)

蛋白质信息 (UniProt)

脯氨酰4-羟化酶亚基α-1 (4-PH alpha-1) (EC 1.14.11.2) (前胶原-脯氨酸,2-氧戊二酸-4-双加氧酶亚基α-1)

P13674

功能描述

催化胶原蛋白和其他蛋白质中 -Xaa-Pro-Gly- 序列中 4-羟脯氨酸的翻译后形成。 {ECO:0000269|PubMed:9211872}。

组织特异性

Expressed in the heart, liver, skeletal muscle, kidney, placenta, lung and pancreas.

亚细胞定位

Endoplasmic reticulum lumen.

关键词

3D-structure Alternative splicing Dioxygenase Endoplasmic reticulum Glycoprotein Iron Metal-binding Oxidoreductase Proteomics identification Reference proteome

外部链接

UniProt: P13674
NCBI Gene