P2RY13 Q9BPV8

P2Y嘌呤受体13 (P2Y13) (G蛋白偶联受体86) (G蛋白偶联受体94)

功能描述

ADP受体。与G(i)蛋白偶联。可能在造血和免疫系统中发挥作用。 {ECO:0000269|PubMed:11546776}。

组织特异性

Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined.

亚细胞定位

Cell membrane; Multi-pass membrane protein.