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OSGEPL1 Q9H4B0

线粒体tRNA N6-腺苷苏氨酰氨基甲酰转移酶 (EC 2.3.1.234) (N6-L-苏氨酰氨基甲酰腺嘌呤合酶) (t(6)A合酶) (O-唾液酸糖蛋白内肽酶样蛋白1) (OSGEP样蛋白1) (t(6)A37苏氨酰氨基甲酰腺苷生物合成蛋白OSGEPL1) (tRNA苏氨酰氨基甲酰腺苷生物合成蛋白OSGEPL1)

蛋白质信息 (UniProt)

线粒体tRNA N6-腺苷苏氨酰氨基甲酰转移酶 (EC 2.3.1.234) (N6-L-苏氨酰氨基甲酰腺嘌呤合酶) (t(6)A合酶) (O-唾液酸糖蛋白内肽酶样蛋白1) (OSGEP样蛋白1) (t(6)A37苏氨酰氨基甲酰腺苷生物合成蛋白OSGEPL1) (tRNA苏氨酰氨基甲酰腺苷生物合成蛋白OSGEPL1)

Q9H4B0

功能描述

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. {ECO:0000255|HAMAP-Rule:MF_03179, ECO:0000269|PubMed:29760464, ECO:0000269|PubMed:32047918}.

组织特异性

Widely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus.

亚细胞定位

Mitochondrion

关键词

Acetylation Acyltransferase Alternative splicing Metal-binding Mitochondrion Proteomics identification Reference proteome Transferase Transit peptide tRNA processing