OGFOD1 Q8N543

脯氨酰3-羟化酶 OGFOD1 (EC 1.14.11.-) (含2-氧戊二酸和铁依赖性加氧酶结构域蛋白1) (终止和多聚腺苷酸化1同源物) (uS12脯氨酰3-羟化酶)

蛋白质信息 (UniProt)

脯氨酰3-羟化酶 OGFOD1 (EC 1.14.11.-) (含2-氧戊二酸和铁依赖性加氧酶结构域蛋白1) (终止和多聚腺苷酸化1同源物) (uS12脯氨酰3-羟化酶)

Q8N543

功能描述

脯氨酰3-羟化酶，催化核糖体小亚基uS12 (RPS23)的'Pro-62'发生3-羟基化，从而调节蛋白质翻译终止效率。参与应激颗粒形成。 {ECO:0000269|PubMed:20154146, ECO:0000269|PubMed:24550447, ECO:0000269|PubMed:24550462}.

亚细胞定位

[Isoform 1]: Cytoplasm. Nucleus. Note=Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.

关键词

3D-structure Alternative splicing Cytoplasm Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Proteomics identification Reference proteome

外部链接

UniProt: Q8N543

NCBI Gene

GeneCards