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NPY4R P50391

神经肽Y受体4型 (NPY4-R) (胰多肽受体1) (PP1)

蛋白质信息 (UniProt)

神经肽Y受体4型 (NPY4-R) (胰多肽受体1) (PP1)

P50391

功能描述

PPY/胰多肽/PP、NPY/神经肽Y和PYY/肽YY的G蛋白偶联受体,与cAMP负偶联 (PubMed:7493937, PubMed:7592911)。这些多肽及其衍生物的亲和力排序为 PP, PP (2-36) 和 [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY 和 [Leu-31, Pro-34] NPY > NPY > PYY (3-36) 和 NPY (2-36) > PP (13-36) > PP (31-36) > NPY 游离酸。 {ECO:0000269|PubMed:7493937, ECO:0000269|PubMed:7592911}。

组织特异性

Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine.

亚细胞定位

Cell membrane

关键词

3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome