NPY2R P49146

神经肽Y受体2型 (NPY2-R) (NPY-Y2受体) (Y2受体)

功能描述

神经肽Y和肽YY的受体。该受体对胰多肽的亲和力排序为 PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY 和 NPY 游离酸。

组织特异性

High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.

亚细胞定位

Cell membrane; Multi-pass membrane protein.