NLRP7 Q8WX94

含NACHT、LRR和PYD结构域蛋白7 (核苷酸结合寡聚化结构域蛋白12) (含PYRIN的APAF1样蛋白3)

蛋白质信息 (UniProt)

含NACHT、LRR和PYD结构域蛋白7 (核苷酸结合寡聚化结构域蛋白12) (含PYRIN的APAF1样蛋白3)

Q8WX94

功能描述

抑制CASP1/caspase-1依赖性的IL1B分泌。 {ECO:0000269|PubMed:15817483}。

组织特异性

Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.

关键词

3D-structure Alternative splicing ATP-binding Disease variant Leucine-rich repeat Nucleotide-binding Proteomics identification Reference proteome Repeat

外部链接

UniProt: Q8WX94

NCBI Gene

GeneCards