NIT2 Q9NQR4

Ω-酰胺酶 NIT2 (EC 3.5.1.3) (腈水解酶同源物 2)

功能描述

具有ω-酰胺酶活性 (PubMed:19595734, PubMed:22674578)。ω-酰胺酶的作用是通过分别将2-氧代戊二酰胺酸和2-氧代琥珀酰胺酸转化为生物学上有用的2-氧代戊二酸和草酰乙酸，从而去除潜在的有毒中间体 (PubMed:19595734)。 {ECO:0000269|PubMed:19595734, ECO:0000269|PubMed:22674578}。

组织特异性

Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon.

亚细胞定位

Cytoplasm