NAV3 Q8IVL0

神经元导航蛋白3 (孔膜和/或丝状相互作用样蛋白1) (Steerin-3) (Unc-53同源物3) (unc53H3)

蛋白质信息 (UniProt)

神经元导航蛋白3 (孔膜和/或丝状相互作用样蛋白1) (Steerin-3) (Unc-53同源物3) (unc53H3)

Q8IVL0

功能描述

参与微管细胞骨架组织，并在细胞迁移中发挥作用 (PubMed:21471154, PubMed:38977784)。 {ECO:0000269|PubMed:21471154, ECO:0000269|PubMed:38977784}。

组织特异性

Present in activated T-cells but not in resting T-cells (at protein level) (PubMed:16166283). Highly expressed in brain (PubMed:12079279, PubMed:15158073). Expressed at low levels in heart and placenta (PubMed:15158073). Down-regulated in primary neuroblastoma (PubMed:12062803).

亚细胞定位

Nucleus outer membrane

关键词

Alternative splicing Chromosomal rearrangement Coiled coil Cytoplasm Cytoskeleton Disease variant Intellectual disability Membrane Nucleus Phosphoprotein

外部链接

UniProt: Q8IVL0

NCBI Gene

GeneCards