MYO9A B2RTY4

非典型肌球蛋白-IXa (非典型肌球蛋白-9a)

蛋白质信息 (UniProt)

非典型肌球蛋白-IXa (非典型肌球蛋白-9a)

B2RTY4

功能描述

肌球蛋白是具有ATPase活性的肌动蛋白马达分子。非典型肌球蛋白参与细胞内运动。通过刺激神经元中Rho的GTPase活性来调节Rho。神经突分支和运动神经元轴突导向的调控所必需(By similarity)。 {ECO:0000250|UniProtKB:Q8C170, ECO:0000250|UniProtKB:Q9Z1N3}。

组织特异性

Found to be expressed in testis and placenta and at lower levels in all the examined tissues with the exception of liver (PubMed:10409426). Isoform 5: Found in leukocytes but not in brain, retina or testis (PubMed:10409426).

亚细胞定位

Membrane

关键词

Actin-binding Alternative splicing ATP-binding Cell projection Coiled coil Congenital myasthenic syndrome Cytoplasm Disease variant GTPase activation Membrane

外部链接

UniProt: B2RTY4

NCBI Gene

GeneCards