MUC17 Q685J3

黏蛋白-17 (MUC-17) (小肠黏蛋白-3) (MUC-3)

功能描述

可能在维持粘膜表面的稳态中发挥作用。 {ECO:0000269|PubMed:17990980}。

组织特异性

Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers.

亚细胞定位

[Isoform 1]: Cell membrane; Single-pass membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted