MSH5 O43196

MutS蛋白同源物5 (hMSH5)

蛋白质信息 (UniProt)

MutS蛋白同源物5 (hMSH5)

O43196

功能描述

参与DNA错配修复和减数分裂重组过程。在减数分裂期间促进同源物之间的交叉（通过相似性）。{ECO:0000250}。

组织特异性

Widely expressed, with high levels in testis and ovary, including granulosa cells (PubMed:28175301, PubMed:9740671). Also expressed in fetal ovary and adrenal gland (PubMed:28175301).

关键词

Alternative splicing ATP-binding Disease variant DNA damage DNA repair DNA-binding Meiosis Nucleotide-binding Premature ovarian failure Proteomics identification

外部链接

UniProt: O43196

NCBI Gene

GeneCards