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MPP3 Q13368

MAGUK p55亚家族成员3 (Discs large同源物3) (蛋白MPP3)

蛋白质信息 (UniProt)

MAGUK p55亚家族成员3 (Discs large同源物3) (蛋白MPP3)

Q13368

功能描述

通过将CADM1连接至DLG1和phosphoinositide-3-kinase (PI3K)的调节亚基,参与经phosphoinositide-3-kinase (PI3K)通路的细胞铺展 (PubMed:24503895)。稳定质膜上的HTR2C并防止其脱敏。可能参与粘附连接的维持 (By similarity)。 {ECO:0000250|UniProtKB:O88910, ECO:0000269|PubMed:24503895}.

组织特异性

Expressed in retina (at protein level) at the subapical region (SAR) adjacent to adherens junctions at the OLM, and at the OPL.

亚细胞定位

Cell membrane

关键词

Alternative splicing Cell junction Cell membrane Membrane Phosphoprotein Proteomics identification Reference proteome Repeat SH3 domain