MARCO Q9UEW3

巨噬细胞受体MARCO (具有胶原结构的巨噬细胞受体) (A类清道夫受体成员2)

功能描述

模式识别受体 (PRR)，结合革兰氏阳性和革兰氏阴性细菌 (PubMed:9468508)。也在肺泡巨噬细胞结合未调理颗粒中发挥作用 (By similarity)。结合分泌球蛋白 SCGB3A2 (PubMed:12847263)。 {ECO:0000250|UniProtKB:Q9WUB9, ECO:0000269|PubMed:12847263, ECO:0000269|PubMed:9468508}。

组织特异性

Expressed in alveolar macrophages (at protein level). Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen (PubMed:9468508).

亚细胞定位

Cell membrane