MAP1S Q66K74

微管相关蛋白1S (MAP-1S) (BPY2相互作用蛋白1) (微管相关蛋白8) (可变电荷Y染色体2相互作用蛋白1) (VCY2相互作用蛋白1) (VCY2IP-1) [切割为：MAP1S重链；MAP1S轻链]

功能描述

微管相关蛋白，介导线粒体聚集，导致细胞死亡和基因组破坏(MAGD)。在将微管组织中心锚定到中心体中起作用。结合DNA。在细胞凋亡中起作用。参与微管束的形成(By similarity)。{ECO:0000250, ECO:0000269|PubMed:15899810, ECO:0000269|PubMed:17234756}。

组织特异性

Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle.

亚细胞定位

Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton