膜相关鸟苷酸激酶、WW和PDZ结构域包含蛋白1 (Atrophin-1相互作用蛋白3) (AIP-3) (BAI1相关蛋白1) (BAP-1) (膜相关鸟苷酸激酶倒置1) (MAGI-1) (三核苷酸重复包含基因19蛋白) (WW结构域包含蛋白3) (WWP3)
膜相关鸟苷酸激酶、WW和PDZ结构域包含蛋白1 (Atrophin-1相互作用蛋白3) (AIP-3) (BAI1相关蛋白1) (BAP-1) (膜相关鸟苷酸激酶倒置1) (MAGI-1) (三核苷酸重复包含基因19蛋白) (WW结构域包含蛋白3) (WWP3)
Q96QZ7功能描述
通过与AMOTL2和CDH5相互作用，在内皮细胞中将肌动蛋白纤维偶联到细胞连接中 (By similarity)。可能通过调节ASIC3在细胞表面的表达来调节酸诱导的ASIC3电流 (By similarity)。 {ECO:0000250, ECO:0000250|UniProtKB:Q6RHR9}。
组织特异性
Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain.
亚细胞定位
Cell junction, tight junction
关键词