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MAGED4 Q96JG8

黑色素瘤相关抗原D4 (MAGE-D4抗原) (MAGE-E1抗原)

蛋白质信息 (UniProt)

黑色素瘤相关抗原D4 (MAGE-D4抗原) (MAGE-E1抗原)

Q96JG8

功能描述

可能增强含RING型锌指结构的E3泛素-蛋白连接酶的泛素连接酶活性。推测通过在E3:底物复合物处招募和/或稳定Ubl结合酶(E2)起作用。 {ECO:0000269|PubMed:20864041}。

组织特异性

Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples.

关键词

Alternative splicing Proteomics identification Reference proteome Tumor antigen Ubl conjugation pathway