LY96 Q9Y6Y9

淋巴细胞抗原96 (Ly-96) (ESOP-1) (蛋白MD-2)

蛋白质信息 (UniProt)

淋巴细胞抗原96 (Ly-96) (ESOP-1) (蛋白MD-2)

Q9Y6Y9

功能描述

结合细菌脂多糖(LPS) (PubMed:17569869, PubMed:17803912)。与TLR4协同参与针对细菌脂多糖(LPS)的先天免疫应答，并与TLR2协同参与针对革兰氏阳性和革兰氏阴性细菌细胞壁成分的应答 (PubMed:11160242, PubMed:11593030)。增强TLR4依赖性的NF-kappa-B激活 (PubMed:10359581)。同时表达LY96和TLR4的细胞，而非仅表达TLR4的细胞，对LPS有应答 (PubMed:10359581)。 {ECO:0000269|PubMed:10359581, ECO:0000269|PubMed:11160242, ECO:0000269|PubMed:11593030, ECO:0000269|PubMed:17569869, ECO:0000269|PubMed:17803912}。

亚细胞定位

Secreted, extracellular space

关键词

3D-structure Alternative splicing Disulfide bond Glycoprotein Immunity Inflammatory response Innate immunity Proteomics identification Reference proteome Secreted

外部链接

UniProt: Q9Y6Y9

NCBI Gene

GeneCards