LRRC17 Q8N6Y2

富含亮氨酸重复序列蛋白17 (p37NB)

功能描述

参与骨稳态。作为RANKL诱导的破骨细胞前体从骨髓前体分化的负调控因子（通过相似性）。{ECO:0000250}。

组织特异性

Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells.

亚细胞定位

Secreted, extracellular space