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LPAR6 P43657

溶血磷脂酸受体6 (LPA受体6) (LPA-6) (油酰-L-α-溶血磷脂酸受体) (P2Y嘌呤受体5) (P2Y5) (嘌呤受体5) (RB内含子编码G蛋白偶联受体)

蛋白质信息 (UniProt)

溶血磷脂酸受体6 (LPA受体6) (LPA-6) (油酰-L-α-溶血磷脂酸受体) (P2Y嘌呤受体5) (P2Y5) (嘌呤受体5) (RB内含子编码G蛋白偶联受体)

P43657

功能描述

结合油酰-L-α-溶血磷脂酸 (LPA)。细胞内cAMP参与受体激活。对维持毛发生长和质地很重要。 {ECO:0000269|PubMed:18297070}。

组织特异性

Expressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes.

亚细胞定位

Cell membrane

关键词

3D-structure Cell membrane Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Hypotrichosis Lipoprotein Membrane Palmitate