返回首页

LGALS13 Q9UHV8

半乳糖苷结合可溶性凝集素13 (Galectin-13) (Gal-13) (胎盘组织蛋白13) (PP13) (胎盘蛋白13)

蛋白质信息 (UniProt)

半乳糖苷结合可溶性凝集素13 (Galectin-13) (Gal-13) (胎盘组织蛋白13) (PP13) (胎盘蛋白13)

Q9UHV8

功能描述

结合β-半乳糖苷和乳糖。T细胞凋亡的强诱导剂 (PubMed:10527825, PubMed:19497882)。对鸡红细胞具有血凝活性 (PubMed:29343868)。作为铁死亡的激活剂:由铁死亡细胞分泌,并通过减少SLC7A11在质膜上的定位发挥作用 (PubMed:40246981)。 {ECO:0000269|PubMed:10527825, ECO:0000269|PubMed:19497882, ECO:0000269|PubMed:29343868, ECO:0000269|PubMed:40246981}。

组织特异性

Detected in adult and fetal spleen, fetal kidney, adult urinary bladder and placenta. Placental expression originates predominantly from the syncytiotrophoblast.

亚细胞定位

Cytoplasm

关键词

3D-structure Apoptosis Cytoplasm Disulfide bond Hemagglutinin Lectin Nucleus Proteomics identification Reference proteome Secreted