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LAMA2 P24043

层粘连蛋白α2亚基 (层粘连蛋白M链) (层粘连蛋白-12亚基α) (层粘连蛋白-2亚基α) (层粘连蛋白-4亚基α) (Meronsin重链)

蛋白质信息 (UniProt)

层粘连蛋白α2亚基 (层粘连蛋白M链) (层粘连蛋白-12亚基α) (层粘连蛋白-2亚基α) (层粘连蛋白-4亚基α) (Meronsin重链)

P24043

功能描述

通过高亲和力受体与细胞结合,laminin被认为通过与其他细胞外基质成分相互作用,在胚胎发育过程中介导细胞附着、迁移和组织形成。

组织特异性

Placenta, striated muscle, peripheral nerve, cardiac muscle, pancreas, lung, spleen, kidney, adrenal gland, skin, testis, meninges, choroid plexus, and some other regions of the brain; not in liver, thymus and bone.

亚细胞定位

Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.

关键词

3D-structure Basement membrane Cell adhesion Coiled coil Congenital muscular dystrophy Direct protein sequencing Disease variant Disulfide bond Extracellular matrix Glycoprotein