KRT73 Q86Y46

II型细胞骨架角蛋白73 (细胞角蛋白-73) (CK-73) (角蛋白-73) (K73) (II型内根鞘特异性角蛋白-K6irs3) (II型角蛋白 Kb36)

功能描述

在毛发形成中发挥作用。毛囊内根鞘(IRS)中角蛋白中间丝的特异性组分 (Probable)。 {ECO:0000305}。

组织特异性

Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level).