KRT72 Q14CN4

II型细胞骨架角蛋白72 (细胞角蛋白-72) (CK-72) (角蛋白-72) (K72) (II型内根鞘特异性角蛋白-K6irs2) (II型角蛋白Kb35)

功能描述

在毛发形成中发挥作用。毛囊内根鞘(IRS)中角蛋白中间丝的特异性组分 (Probable)。 {ECO:0000305}。

组织特异性

Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level).