KRT28 Q7Z3Y7

I型细胞骨架角蛋白28 (细胞角蛋白-28) (CK-28) (角蛋白-25D) (K25D) (角蛋白-28) (K28) (I型内根鞘特异性角蛋白-K25irs4)

功能描述

对于内根鞘(irs)中I型和II型角蛋白复合物的正确组装以及角蛋白中间丝的形成至关重要。 {ECO:0000250|UniProtKB:A6BLY7}。

组织特异性

Strongly expressed in skin and scalp, and weak expression observed in thymus. In the hair follicle, expressed in Henle layer, Huxley layer and in the irs cuticle. Expression extends from the bulb region up to the point of differentiation into the three layers. Also present in the medulla of beard hair (at protein level).

亚细胞定位

Cytoplasm