KERA O60938

角膜蛋白 (KTN) (硫酸角质素蛋白聚糖角膜蛋白)

蛋白质信息 (UniProt)

角膜蛋白 (KTN) (硫酸角质素蛋白聚糖角膜蛋白)

O60938

功能描述

可能在发育和维持角膜透明度以及基质基质的结构方面起重要作用。 {ECO:0000305|PubMed:10802664, ECO:0000305|PubMed:11726611}。

组织特异性

Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664).

亚细胞定位

Secreted, extracellular space, extracellular matrix

关键词

Disease variant Disulfide bond Extracellular matrix Glycoprotein Leucine-rich repeat Proteoglycan Proteomics identification Reference proteome Repeat Secreted

外部链接

UniProt: O60938

NCBI Gene

GeneCards