Kell血型糖蛋白 (EC 3.4.24.-) (CD抗原 CD238)
Kell血型糖蛋白 (EC 3.4.24.-) (CD抗原 CD238)
P23276功能描述
具有内皮素-3转化酶活性的锌内肽酶。切割EDN1、EDN2和EDN3，对EDN3有明显偏好。 {ECO:0000269|PubMed:10438732}。
组织特异性
Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.
亚细胞定位
Cell membrane; Single-pass type II membrane protein. Note=Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
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