ITPKA P23677

肌醇三磷酸3-激酶A (EC 2.7.1.127) (肌醇1,4,5-三磷酸3-激酶A) (IP3 3-激酶A) (IP3K A) (InsP 3-激酶A)

蛋白质信息 (UniProt)

肌醇三磷酸3-激酶A (EC 2.7.1.127) (肌醇1,4,5-三磷酸3-激酶A) (IP3 3-激酶A) (IP3K A) (InsP 3-激酶A)

P23677

功能描述

催化1D-myo-inositol 1,4,5-trisphosphate (InsP3)磷酸化为1D-myo-inositol 1,3,4,5-tetrakisphosphate，并参与钙稳态的调节。 {ECO:0000269|PubMed:12747803, ECO:0000269|PubMed:15350214, ECO:0000269|PubMed:1847047}.

组织特异性

Expressed in brain.

亚细胞定位

Cytoplasm, cytoskeleton

关键词

3D-structure ATP-binding Calmodulin-binding Cytoplasm Cytoskeleton Kinase Methylation Nucleotide-binding Phosphoprotein Proteomics identification

外部链接

UniProt: P23677

NCBI Gene

GeneCards