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IL13RA1 P78552

白细胞介素-13受体亚基α-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (癌/睾丸抗原19) (CT19) (CD抗原CD213a1)

蛋白质信息 (UniProt)

白细胞介素-13受体亚基α-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (癌/睾丸抗原19) (CT19) (CD抗原CD213a1)

P78552

功能描述

以低亲和力结合白细胞介素-13 (IL13)。与IL4RA共同形成IL13的功能性受体。也可作为白细胞介素-4 (IL4)信号传导中常见细胞因子受体γ链的替代辅助蛋白,但不能替代IL2RG在增强白细胞介素-2 (IL2)结合活性方面的功能。

组织特异性

Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.

亚细胞定位

Membrane; Single-pass type I membrane protein.

关键词

3D-structure Alternative splicing Disulfide bond Glycoprotein Membrane Proteomics identification Receptor Reference proteome Repeat Signal