飞马锌指蛋白 (Ikaros家族锌指蛋白5)
飞马锌指蛋白 (Ikaros家族锌指蛋白5)
Q9H5V7功能描述
转录抑制因子，结合核心5'GNNTGTNG-3' DNA共有序列 (PubMed:10978333, PubMed:31217188)。参与巨核细胞分化。 {ECO:0000269|PubMed:10978333, ECO:0000269|PubMed:31217188}。
组织特异性
Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.
亚细胞定位
Nucleus
关键词