鞭毛内运输蛋白74同源物 (毛细血管形态发生基因1蛋白) (CMG-1) (含卷曲螺旋结构域蛋白2)
鞭毛内运输蛋白74同源物 (毛细血管形态发生基因1蛋白) (CMG-1) (含卷曲螺旋结构域蛋白2)
Q96LB3功能描述
鞭毛内运输（IFT）复合体B的组分：与IFT81一起，形成微管蛋白结合模块，特异性介导微管蛋白在纤毛内的运输 (PubMed:23990561)。通过其碱性区域结合β-微管蛋白 (PubMed:23990561)。纤毛发生所必需 (PubMed:23990561)。精子发生过程中的鞭毛形成所必需 (PubMed:33689014)。 {ECO:0000269|PubMed:23990561, ECO:0000269|PubMed:33689014}。
组织特异性
Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen (PubMed:11683410). Detected in sperm (at protein level) (PubMed:33689014).
亚细胞定位
Cell projection, cilium
关键词