HTT P42858

亨廷顿蛋白 (亨廷顿病蛋白) (HD蛋白) [切割为：亨廷顿蛋白，N端肉豆蔻酰化片段]

功能描述

[Huntingtin]: 可能在微管介导的运输或囊泡功能中发挥作用。; FUNCTION: [Huntingtin, myristoylated N-terminal fragment]: 促进自噬囊泡的形成。 {ECO:0000269|PubMed:24459296}。

组织特异性

Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation.

亚细胞定位

[Huntingtin]: Cytoplasm