HNF1B P35680

肝细胞核因子1-β (HNF-1-beta) (HNF-1B) (同源蛋白LFB3) (转录因子2) (TCF-2) (变异肝核因子1) (vHNF1)

蛋白质信息 (UniProt)

肝细胞核因子1-β (HNF-1-beta) (HNF-1B) (同源蛋白LFB3) (转录因子2) (TCF-2) (变异肝核因子1) (vHNF1)

P35680

功能描述

结合反向回文序列5'-GTTAATNATTAAC-3'的转录因子 (PubMed:17924661, PubMed:7900999)。结合PLAU基因cAMP调节单元中的FPC元件 (By similarity)。共激活因子PCBD1可增强其转录活性 (PubMed:24204001)。 {ECO:0000250|UniProtKB:Q03365, ECO:0000269|PubMed:17924661, ECO:0000269|PubMed:24204001, ECO:0000269|PubMed:7900999}。

亚细胞定位

Nucleus.

关键词

3D-structure Activator Alternative splicing Diabetes mellitus Disease variant DNA-binding Homeobox Nucleus Phosphoprotein Proteomics identification

外部链接

UniProt: P35680

NCBI Gene

GeneCards