返回首页

HCAR1 Q9BXC0

羟基羧酸受体1 (G蛋白偶联受体104) (G蛋白偶联受体81)

蛋白质信息 (UniProt)

羟基羧酸受体1 (G蛋白偶联受体104) (G蛋白偶联受体81)

Q9BXC0

功能描述

作为L-乳酸的受体,并通过G(i)蛋白介导的途径介导其抗脂解作用。 {ECO:0000269|PubMed:19047060}。

组织特异性

Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus.

亚细胞定位

Cell membrane

关键词

3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer