GYG1 P46976

糖原蛋白-1 (GN-1) (GN1) (EC 2.4.1.186)

蛋白质信息 (UniProt)

糖原蛋白-1 (GN-1) (GN1) (EC 2.4.1.186)

P46976

功能描述

Glycogenin与glycogen synthase及glycogen branching enzyme共同参与glycogen生物合成过程。它催化形成短的alpha (1,4)-glucosyl链，该链通过glucose 1-O-tyrosyl连接共价附着于内部tyrosine残基，这些链作为glycogen synthase催化的延伸反应的引物。 {ECO:0000269|PubMed:22160680, ECO:0000269|PubMed:30356213}。

组织特异性

Highly expressed in skeletal muscle and heart, with lower levels in brain, lung, kidney and pancreas.

亚细胞定位

Cytoplasm

关键词

3D-structure Acetylation Alternative splicing Cytoplasm Disease variant Glycogen biosynthesis Glycogen storage disease Glycoprotein Manganese Metal-binding

外部链接

UniProt: P46976

NCBI Gene

GeneCards