GUCY1A2 P33402

可溶性鸟苷酸环化酶α-2亚基 (GCS-alpha-2) (EC 4.6.1.2)

蛋白质信息 (UniProt)

可溶性鸟苷酸环化酶α-2亚基 (GCS-alpha-2) (EC 4.6.1.2)

P33402

功能描述

结合beta-1亚基后具有鸟苷酸环化酶活性。; FUNCTION: Isoform 2作为鸟苷酸环化酶活性的负调节因子，因为它与beta亚基形成无功能的异源二聚体。

组织特异性

Isoform 1 is expressed in fetal brain, liver, colon, endothelium and testis. Isoform 2 is expressed only in liver, colon and endothelium.

亚细胞定位

Cytoplasm.

关键词

Alternative splicing cGMP biosynthesis Cytoplasm GTP-binding Lyase Nucleotide-binding Proteomics identification Reference proteome

UniProt: P33402

NCBI Gene

GeneCards