G蛋白偶联受体26
G蛋白偶联受体26
Q8NDV2功能描述
孤儿受体。显示出显著水平的组成型活性。其效应由G(s)-alpha蛋白介导,该蛋白刺激腺苷酸环化酶,导致细胞内cAMP升高。 {ECO:0000269|PubMed:17363172}。
组织特异性
Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma.
亚细胞定位
Cell membrane; Multi-pass membrane protein.
关键词