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GPR26 Q8NDV2

G蛋白偶联受体26

蛋白质信息 (UniProt)

G蛋白偶联受体26

Q8NDV2

功能描述

孤儿受体。显示出显著水平的组成型活性。其效应由G(s)-alpha蛋白介导,该蛋白刺激腺苷酸环化酶,导致细胞内cAMP升高。 {ECO:0000269|PubMed:17363172}。

组织特异性

Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma.

亚细胞定位

Cell membrane; Multi-pass membrane protein.

关键词

Cell membrane Disulfide bond G-protein coupled receptor Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix