GIMAP4 Q9NUV9

GTPase IMAP家族成员4 (免疫相关核苷酸1蛋白) (IAN-1) (hIAN1) (免疫相关蛋白4)

功能描述

在胸腺细胞发育过程中，可能在细胞凋亡调节中发挥作用 (By similarity)。GTPase，对 GDP 的亲和力高于 GTP。{ECO:0000250, ECO:0000250|UniProtKB:Q99JY3}。

组织特异性

Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.

亚细胞定位

Cytoplasm, cytosol