GAPT Q8N292

GAPT蛋白 (GRB2结合衔接蛋白，跨膜) (生长因子受体结合蛋白2结合衔接蛋白，跨膜)

功能描述

通过B细胞受体刺激后负向调节B细胞增殖。可能在边缘区(MZ) B细胞的维持中发挥重要作用 (By similarity)。 {ECO:0000250}。

组织特异性

Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested. Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells.

亚细胞定位

Cell membrane