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FTMT Q8N4E7

铁蛋白,线粒体 (EC 1.16.3.1)

蛋白质信息 (UniProt)

铁蛋白,线粒体 (EC 1.16.3.1)

Q8N4E7

功能描述

催化亚铁(II)氧化为铁(III),并以可溶、无毒且易利用的形式储存铁 (PubMed:11323407, PubMed:15201052)。对铁稳态很重要 (PubMed:11323407, PubMed:15201052)。铁以亚铁形式被摄取,氧化后以氢氧化铁形式沉积 (PubMed:11323407, PubMed:15201052)。 {ECO:0000269|PubMed:11323407, ECO:0000269|PubMed:15201052}。

组织特异性

Detected in testis and erythroleukemia. Expression is very low or not detectable in brain, colon, heart, kidney, liver, lung, muscle, placental, spleen and small intestine.

亚细胞定位

Mitochondrion

关键词

3D-structure Iron Iron storage Metal-binding Mitochondrion Oxidoreductase Proteomics identification Reference proteome Transit peptide